
Highlights
Age Groups Seen
- Adults
- Adults 65 and up
Languages
- English
Gender
MaleAbout James Frederick Littles, Jr.
Dr. James Littles, Jr., is a native of Florence, South Carolina. He earned his medical degree from Howard University College of Medicine and completed his specialty training in Metropolitan Detroit, Michigan. Dr. Littles previously served as a faculty member at the University of Michigan Medical School, where he contributed to clinical education and patient care.
His clinical interests and areas of expertise include gastrointestinal cancers, breast cancer, prostate cancer, osteoarthritis and the use of stereotactic body radiation therapy (SBRT) for lung cancer and oligometastatic disease. Dr. Littles is committed to delivering patient-centered, evidence-based care while advancing precision treatment approaches in oncology. Dr. Littles believes in practicing medicine with a servant's heart.
Outside of medicine, Dr. Littles enjoys spending time with his family, church community and friends. His personal interests include reading nonfiction literature, experiencing helicopter tours and watching sports and historical programming on YouTube.
Video
Locations
- Prisma Health Cancer Institute – Richland Radiation Oncology 7MP
- 7 Richland Medical Park Drive, Suite 104, Columbia, SC 29203
- Get Directions
Expertise
Education
- Medical School: Howard University
- Residency: William Beaumont University Hospital, Royal Oak, Radiation Oncology
Board Certifications
- Radiation Oncology: American Board of Radiology
Insurance
- Absolute Total Care - Ambetter
- Absolute Total Care (Centene)
- Aetna
- Aetna Medicare
- Allwell Medicare - Absolute Total Care
- BCBS
- BCBS Blue Essentials
- BCBS PPC
- BCBSSC Blue Reedy Exchange Product (Upstate)
- BCBSSC State Health Plan (PEBA)
- BlueChoice Health Plan
- BlueChoice Medicaid - Healthy Blue
- BlueChoiceMyChoice Advantage
- Carelon Behavioral Health
- Cigna
- Cigna Medicare
- Companion Benefit Alternatives
- CorVel Workers Compensation
- Evernorth Behavioral Health
- FirstHealth (Aetna)
- Healthy Connections
- Humana - Healthy Horizons
- Humana Choice Care
- Humana Medicare
- Liberty Advantage
- Logistics Health
- Magellan
- MedCost
- Medicare (Traditional Fee-for-Service)
- Molina
- Molina Medicaid
- Multiplan/PHCS
- NHC Advantage
- Optum Behavioral Health
- Promise Health Plan
- SC Medicaid Healthy Connections
- Select Health Medicare
- Select Heath (First Choice)
- Spectera
- TriCare
- UnitedHealthcare Medicare Advantage
- Veterans Affairs Community Care Network - VACCN
- Wellcare (Centene)
Ratings & Reviews
4.8 out of 5
59 ratings, 12 reviewsThe Patient Satisfaction Rating is derived from patient surveys based on the likelihood to recommend this provider’s office.
- 5 out of 5 starsReviewed on 2/20/2026
...couldn't think of anything I would of changed, and I appreciate all of your generosity, support and kindness,God Bless You all!!!
- 5 out of 5 starsReviewed on 2/14/2026
All good. Thank you.
- 5 out of 5 starsReviewed on 2/4/2026
Very nice doctor and nurse
- 5 out of 5 starsReviewed on 1/26/2026
Dr. Littles was wonderful. He was very easy to talk to and explain things so I could understand. Both he and his nurse were very personable and made me feel very comfortable. Dr. Littles took his time which I appreciated. Dr. Littles impressed both myself and my daughter. We can't say enough good things about him.
- 5 out of 5 starsReviewed on 1/12/2026
All good.
- 5 out of 5 starsReviewed on 1/5/2026
I was thoroughly satisfied with my overall treatment
- 5 out of 5 starsReviewed on 11/23/2025
My visit went well.
- 5 out of 5 starsReviewed on 11/4/2025
Definitely their human staff is excellent, I could only thank them for their deep ethics and love for what they do
- 5 out of 5 starsReviewed on 10/15/2025
No improvement except for no customer service or patient care.
- 5 out of 5 starsReviewed on 7/28/2025
I have no regret and no response for how you can improve. I had superb care. I'm very satisfied. And I'm grateful for Dr. Littles and his staff.
- 5 out of 5 starsReviewed on 5/31/2025
I was satisfied with my visit.
- 5 out of 5 starsReviewed on 5/29/2025
Couldn't ask for better folks to take care of me through radiation treatments. What a great group of folks!!