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James Frederick Littles, Jr.

James Frederick Littles, Jr., MD

Radiation Oncology

Referral Required

Highlights

Age Groups Seen

  • Adults
  • Adults 65 and up

Languages

  • English

Gender

Male

About James Frederick Littles, Jr.

Dr. James Littles, Jr., is a native of Florence, South Carolina. He earned his medical degree from Howard University College of Medicine and completed his specialty training in Metropolitan Detroit, Michigan. Dr. Littles previously served as a faculty member at the University of Michigan Medical School, where he contributed to clinical education and patient care.

His clinical interests and areas of expertise include gastrointestinal cancers, breast cancer, prostate cancer, osteoarthritis and the use of stereotactic body radiation therapy (SBRT) for lung cancer and oligometastatic disease. Dr. Littles is committed to delivering patient-centered, evidence-based care while advancing precision treatment approaches in oncology. Dr. Littles believes in practicing medicine with a servant's heart.

Outside of medicine, Dr. Littles enjoys spending time with his family, church community and friends. His personal interests include reading nonfiction literature, experiencing helicopter tours and watching sports and historical programming on YouTube.

Video

Locations

  1. Prisma Health Cancer Institute – Richland Radiation Oncology 7MP
    • 7 Richland Medical Park Drive, Suite 104, Columbia, SC 29203
    • Get Directions

    Expertise

    Education

    • Medical School: Howard University
    • Residency: William Beaumont University Hospital, Royal Oak, Radiation Oncology

    Board Certifications

    • Radiation Oncology: American Board of Radiology

    Insurance

    Note: Please contact your insurance provider to confirm participation
    Search plans
    • Absolute Total Care - Ambetter
    • Absolute Total Care (Centene)
    • Aetna
    • Aetna Medicare
    • Allwell Medicare - Absolute Total Care
    • BCBS
    • BCBS Blue Essentials
    • BCBS PPC
    • BCBSSC Blue Reedy Exchange Product (Upstate)
    • BCBSSC State Health Plan (PEBA)
    • BlueChoice Health Plan
    • BlueChoice Medicaid - Healthy Blue
    • BlueChoiceMyChoice Advantage
    • Carelon Behavioral Health
    • Cigna
    • Cigna Medicare
    • Companion Benefit Alternatives
    • CorVel Workers Compensation
    • Evernorth Behavioral Health
    • FirstHealth (Aetna)
    • Healthy Connections
    • Humana - Healthy Horizons
    • Humana Choice Care
    • Humana Medicare
    • Liberty Advantage
    • Logistics Health
    • Magellan
    • MedCost
    • Medicare (Traditional Fee-for-Service)
    • Molina
    • Molina Medicaid
    • Multiplan/PHCS
    • NHC Advantage
    • Optum Behavioral Health
    • Promise Health Plan
    • SC Medicaid Healthy Connections
    • Select Health Medicare
    • Select Heath (First Choice)
    • Spectera
    • TriCare
    • UnitedHealthcare Medicare Advantage
    • Veterans Affairs Community Care Network - VACCN
    • Wellcare (Centene)

    Ratings & Reviews

    4.8 out of 5

    59 ratings, 12 reviews

    The Patient Satisfaction Rating is derived from patient surveys based on the likelihood to recommend this provider’s office.

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    Likely to Recommend
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      5 out of 5 stars
      Reviewed on 2/20/2026

      ...couldn't think of anything I would of changed, and I appreciate all of your generosity, support and kindness,God Bless You all!!!

      5 out of 5 stars
      Reviewed on 2/14/2026

      All good. Thank you.

      5 out of 5 stars
      Reviewed on 2/4/2026

      Very nice doctor and nurse

      5 out of 5 stars
      Reviewed on 1/26/2026

      Dr. Littles was wonderful. He was very easy to talk to and explain things so I could understand. Both he and his nurse were very personable and made me feel very comfortable. Dr. Littles took his time which I appreciated. Dr. Littles impressed both myself and my daughter. We can't say enough good things about him.

      5 out of 5 stars
      Reviewed on 1/12/2026

      All good.

      5 out of 5 stars
      Reviewed on 1/5/2026

      I was thoroughly satisfied with my overall treatment

      5 out of 5 stars
      Reviewed on 11/23/2025

      My visit went well.

      5 out of 5 stars
      Reviewed on 11/4/2025

      Definitely their human staff is excellent, I could only thank them for their deep ethics and love for what they do

      5 out of 5 stars
      Reviewed on 10/15/2025

      No improvement except for no customer service or patient care.

      5 out of 5 stars
      Reviewed on 7/28/2025

      I have no regret and no response for how you can improve. I had superb care. I'm very satisfied. And I'm grateful for Dr. Littles and his staff.

      5 out of 5 stars
      Reviewed on 5/31/2025

      I was satisfied with my visit.

      5 out of 5 stars
      Reviewed on 5/29/2025

      Couldn't ask for better folks to take care of me through radiation treatments. What a great group of folks!!